In a continuation of the epic story, Dr. Kelson (Ralph Fiennes) finds himself in a shocking new relationship - with consequences that could change the world as they know it - and Spike's (Alfie Williams) encounter with Jimmy Crystal (Jack O'Connell) becomes a nightmare he can't escape. In the world of The Bone Temple, the infected are no longer the greatest threat to survival - the inhumanity of the survivors can be stranger and more terrifying.